March 2011, Vol. 2
eHeartlink is designed to provide general health news and wellness information. This information is not designed to, nor should it, be used as a substitute for professional medical advice. Please consult your physician before undertaking any form of medical treatment or nutrition or exercise program.

Can an infection give you a heart attack?

When you have an infection such as gum disease or pneumonia, chances are youíre most concerned about the symptoms youíre experiencing at the moment. However, mounting evidence suggests that the way the human body reacts to a bacterial or viral infection may put patients at increased risk for heart attack.

When an infection is present, the affected blood vessels and surrounding tissues become inflamed. The signs are redness, swelling, pain and warmth, although they donít always occur together. Scientists are finding that infections that occur in the mouth, lungs or stomach can cause inflammation not only locally but also in the bloodstream.

Inflammation is the bodyís way of signaling the immune system to send infection-fighting cells to a site. However, many scientists now believe that when inflammation occurs in the blood vessels, a dangerous chain of events can be set in motion. The leading suspects are, ironically, the very cells that help the body fight infection.

One theory is that infection-fighting cells release certain chemicals that encourage the growth of plaque (fatty deposits) on artery walls. Blood vessels become narrowed in the spots where plaque collects, increasing the odds that blood flow to the heart may, at some point, become totally blocked. The end result: a heart attack. Another theory is that chemicals released by infection-fighting cells increase the odds that existing plaque will break away as a clot, after which it may become lodged in an artery, blocking blood flow and causing a heart attack.

Why it matters

What does this mean to you? The bad news is that the bacteria that cause such common infections as periodontal disease, stomach ulcers, bronchitis and pneumonia may increase a personís risk of heart attack.

The good news is that aspirin, a drug that many heart-disease patients already take because it helps to prevent blood clots, appears to reduce inflammation in the bloodstream. In recently released guidelines, the American Heart Association recommends low-dose aspirin therapy be considered for anyone with a 10 percent or greater risk of developing cardiovascular disease over the next ten years. All women older than age 65, even those with no other risk factors, should discuss aspirin therapy with their doctors.

A proven link between infection and heart attacks would mean that antibiotics, commonly used to treat bacterial infections, may become a treatment option for patients with heart disease. Already, antibiotics have been shown to reduce inflammation in the bloodstream.

However, researchers have yet to prove that antibiotics actually can prevent heart attacks. Even if that link is made, itís unlikely doctors will start prescribing antibiotics to all patients with risk factors for heart disease.

Why? Because the liberal use of antibiotics already has allowed some infectious organisms to evolve in ways that have made them immune to antibiotics, leaving doctors with no effective treatment for these ďsuper bugs.Ē

In the future, drugs that fight inflammation in the bloodstream may turn out to be treatment options for some patients with heart disease. Even so, experts recommend that people continue to focus on controlling such established risk factors as high cholesterol, high blood pressure, excess weight, sedentary lifestyle, smoking and diabetes.

To learn about heart conditions and treatments available at Deborah Heart and Lung Center, click here.